Alpha lipoic acid (ALA) is one of the most powerful anti-aging, antioxidant, anti-inflammatories available. ALA is called "the universal antioxidant" because it is both fat- and water-soluble.
This means that ALA is easily absorbed through the lipid layers of the skin and works equally well as a free-radical fighter in the cell plasma membrane and in the watery interiors of the cell. This powerful metabolic natural substance has many benefits for skin care, including energy production in skin cells; regeneration of vitamins C and E; inhibiting the activation of transcription factor NF-kB; reduction of cellular inflammation; stimulation of AP-1, which helps remodel collagen; and protection of the skin from free radical inflammation, including sun exposure. Further, it is 400 times stronger than vitamins E and C combined (both of which are renowned for their antioxidant properties).